Princess Nicotine (1909)

Comedic short that pits a smoker against a tiny fairy, brought to life through early special effects, by George Méliès, the pioneer of trick photography.

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(low to high quality versions available)

via the Internet Archive

from a New York Times review:

The nominal plot consists of the Smoker falling asleep, only to have his rest disturbed by two tiny visitors. This provides a framework for the special effects. We see the Smoker asleep in his chair and the fairies emerge onto the table near him. Many of the shots are designed to show the diminutive fairies contrasted against and interacting with much larger objects. The innovative techniques of Princess Nicotine; or, The Smoke Fairy were celebrated in scientific journals and thus were made available to others experimenting with filmed visual tricks. A part of what's fun about Princess Nicotine today is to watch and try to figure out how the amazing shots were created while limited to early cinematic technology.